Here I come with more ideas for a Karma GU. Mainly number and mechanics tweaks, almost no visual work involved. Numbers are symbolic and everything aside from the core ideas are only suggestions.
R - Gathering Fire
Karma has access to a second resource bar: **Prana**. Whenever Karma’s basic abilities interacts with other Champions, she generates Prana, that is consumed upon Mantra activation to achieve bonus effects. Every time Karma generates Prana, Mantra’s cooldown is reduced by 1 second. At full Prana, Karma’s next Mantra cast has no Mana cost.
Q - Inner Flame
Worlds being over, the AP scaling can safely go back to 60% AP.
RQ - Soulflare
Same as current. **Consumes available Prana**, healing allies inside the first impact zone by up to 100 (+50% AP). The post detonation heals for half that amount.
W - Spirit Bond: Tethers Karma to another Champion.
Enemy: Damages and, if the link is not broken, damages again and roots for 1,5 s.
Ally: Karma and the ally receive 20 / 30 / 40 / 50 / 60 AP for the tethered duration.
RW - Sublime Ardor
Enemy: Damages the enemy and heals Karma for 10% (+30% AP) of missing health. If not broken, heals again and roots (no more bonus rooting time). **Consumes available Prana**, burning the target for up to 65 / 140 / 215 / 290 + 60% AP bonus damage over 3 seconds.
Ally: Bonus 15 / 30 / 45 / 60 AP for the duration. **Consumes available Prana**, converting it into % missing Mana restoration.
E - Inspire
Shield power adjusted to 80 / 115 / 150 / 185 / 220 (+55% AP).
RE - Guidance and Defiance
Inspire's target receives bonus shields. After 1 second, the ally ignites, spreading 75% of the initial shield and movement speed values to nearby allies, split among them (Neuro <3). **Consumes available Prana** to cause the ignition to damage foes, up to 80 / 160 / 240 / 320 (+60% AP).
Once more: I'm no game dev. These are just ideas. I'm just a LoL player who have been maining Support Karma since 2015 and that would love to see cool/unique stuff being done to her.