It is literally physically painful and mentally stressful.
If the feeders die, it's no biggie, the fed carry will bail them out if the team has one.
Soon as your fed carry dies, the entire game goes to pot for that team.
Why is it that the player who fixes their ally's screw ups the one who ends up punished the hardest for dying?
The shut down gold is bad enough, but the death timers for dying just once in mid to late game is just overkill.