So I just finished a game and started another. I walked up to use my abilities and nothing happened. I found out all of my settings reverted back to default for no reason. I didn't close my client. I had no errors. It just cleared everything. We lost the game since I had to spend 3 minutes resetting all of my hotkeys and settings, and I still don't know if everything is back the way it needs to be.
Needless to say, it was frustrating, I got flamed and reported for something I had no control over. This patch has some pretty serious bugs so far.