Ping Spikes & Packet Loss Only Ever In League of Legends?!

I have played League of Legends for a while but for the past year, I have had terrible ping spikes and packet loss at random when I try playing this game. I run speedtests and I have 120 Download & 20 Upload so thought maybe the 5G connection was just not that great but when I play other games such as Overwatch, Rainbow Six Siege and more they run perfectly fine. I get no packet loss and I do not lag at all, it says I have a perfect connection. I feel this has to be on Leagues end or something that League has that is not working with what I have. I am not sure and was hoping somebody could help me find a solution.
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