It doesn't matter if you make jokes about being r%%%%%ed within your own social circle. It doesn't matter if you call a team member a r%%%%%, or a short bus rider, or whatever in your voice chat. Those circumstances happen outside of the game; and have no effect on the people within your match. Using slurs like that within the chat, however, cross a significant boundary of what is acceptable and what isn't. As a father of three, and an autistic firstborn child; let me be the first to tell you that it is hurtful, ignorant, and despicable. Thankfully, in a recent match, my teammates were decent human beings and called out the offenders for their wrong-doing.
I guess I'm just asking folks to think for a second before typing out their "smack talk" in game, and realize that there are people behind the champions; and that we should all be doing what we can to defeat the stigma of toxicity and poor community that this wonderful game carries. None of us knows what the person playing along with us may be going through IRL; but we should always strive to encourage an atmosphere of acceptance, tolerance, and appreciation of diversity.