As in, a champion born on the Isles that escaped the Ruination before it could transform or affect them (unlike Thresh/Yorick).
Kalista's lore mentions a "distant white city" at the heart of the Isles; what would someone born and raised there have looked like? How would they dress, or what would their abilities be like? Maybe an old, barefoot monk with ancient magic? Or perhaps a white-hooded priestess with protective spells? I don't know, but I'd love to see a champion from this mysterious place, even if the Ruination happened so long ago.