For example :
Blackfire Torch: +80 ability power. +10% cooldown reduction. Active: UNIQUE: Deals 20% of target champion's maximum health in magic damage over 4 seconds and increases all subsequent magic damage taken by target by 20% (90 second cooldown).
Innervating Locket: +430 health. +450 mana. +10% (Unique) cooldown reduction. Aura: UNIQUE: Nearby allies gain 20 health regeneration and 9 mana regeneration. Passive: UNIQUE: After using an ability, restores 50 health and 20 mana over 2 seconds (3 second cooldown).
Juggernaut: +500 health. +10% cooldown reduction. Passive: UNIQUE – TENACITY: Reduces the duration of stuns, slows, taunts, fears, silences, blinds and immobilizes by 35%. 1400 Gold!!!!!!
Martyrs Gambit: +400 health. +100% base health regeneration. +10% cooldown reduction. Active: UNIQUE: Binds yourself to the target allied champion for the next 3 seconds, redirecting 60% of all damage dealt to them to yourself. 30 second cooldown.
to name a few, theres more of course, like good ol DFG and Feral Flare